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If you’re living with metastatic carcinoid tumors, BYNFEZIA PEN™ gives you

to handle carcinoid symptoms (severe diarrhea/flushing) whenever and wherever you need it

Explore BYNFEZIA PEN™ features >

If you’re living with metastatic carcinoid tumors, BYNFEZIA PEN™ gives you

to handle carcinoid symptoms (severe diarrhea/flushing) whenever and wherever you need it

Explore BYNFEZIA PEN™ features >

BYNFEZIA PEN™ is designed for on-the-go patients:

  • Compact design for ease of use
  • Portable size fits in your hand
  • No refrigeration needed after first use*

No refrigeration needed

No refrigeration needed after first use*

  • No need for ice packs

 

Pens are stable for 28 days at room temperature after first use*

*Store new, unused pens in the refrigerator for up to 24 months from date of manufacture.

Designed for your convenience

Compact and portable

  • Pen size fits in your hand so you can take it with you

 

Multiple dose options

  • Choose 50, 100, 150, or 200 mcg of octreotide acetate

Designed for your comfort and ease of use

Low-volume dose

  • Delivers a low-volume dose of octreotide for greater comfort during self-administration

 

Small-gauge needles

  • Uses shorter (5 mm), smaller-diameter (31 g) pen needles than prefilled octreotide acetate syringes

 

Simple dose dialing

  • Precisely choose the dose you need

Get the latest updates and resources

+IMPORTANT SAFETY INFORMATION

INDICATIONS

BYNFEZIA PEN™ (octreotide acetate) injection is a prescription drug used:

  • Treatment of severe diarrhea/flushing episodes associated with metastatic carcinoid tumors in adult patients
  • Treatment of profuse watery diarrhea associated with vasoactive intestinal peptide tumors (VIPomas) in adult patients
  • To reduce the amount of growth hormone and insulin like growth factor 1 in adult patients with acromegaly who have had inadequate response to or cannot be treated with surgical resection, pituitary irradiation, and bromocriptine mesylate at maximally tolerated doses

LIMITATIONS OF USE

  • In patients with acromegaly, the effect of BYNFEZIA PEN™ to improve symptoms and reduce tumor size and rate of growth has not been determined
  • In patients with carcinoid syndrome and VIPomas, the effect of BYNFEZIA PEN™ on size, rate of growth, and development of metastases has not been determined

IMPORTANT SAFETY INFORMATION

CONTRAINDICATIONS

Do not use BYNFEZIA PEN™ if you are allergic to octreotide.

ADVERSE EFFECTS, WARNINGS AND PRECAUTIONS

BYNFEZIA PEN™ may cause serious adverse effects, including gallstones, high or low blood sugar, thyroid effects, and slow heart rate.  

Tell your healthcare provider if you have any of the following:

  • Signs or symptoms of gallstones (gallbladder/liver problems): May include unexplained pain in your upper right abdomen, sudden pain in your back/right shoulder or between your shoulder blades, yellowing of your skin and whites of your eyes, fever with chills, or severe nausea/vomiting
  • Signs or symptoms of high or low blood sugar: May include increased thirst, urination, appetite, nausea, weakness, or tiredness 
  • Signs or symptoms of low blood sugar: May include nervousness, shakiness, sweating, fast heartbeat, irritability or mood changes, and hunger
  • Signs or symptoms of slow heart rate: May include dizziness or lightheadedness, fainting or near fainting, chest pain, shortness of breath, confusion or memory problems, and weakness or extreme tiredness
  • Signs or symptoms of low thyroid levels: May include unexplained weight gain, cold intolerance, slow heartbeat, severe constipation, unusual/extreme tiredness, growth/lump/swelling on the front of the neck, numbness, or tingling feeling that is not normal

It is not known if BYNFEZIA PEN™ will harm your unborn baby or pass into breast milk.

The most common side effects of BYNFEZIA PEN™ are:

  • Acromegaly patients: Diarrhea, loose stools, nausea and stomach area (abdominal) pain
  • Carcinoid syndrome patients: Headache, dizziness, muscle spasm; side effects were generally similar to those commonly seen with neuroendocrine tumors

Tell your healthcare provider right away if you have signs of an allergic reaction after receiving BYNFEZIA PEN™. Symptoms include swelling of your face, lips or tongue, breathing problems, fainting, dizziness or feeling lightheaded (low blood pressure), itching, skin flushing or redness, rash, or hives.

Before taking BYNFEZIA PEN™, tell your healthcare provider about other medical conditions, especially if you have diabetes, gallbladder, heart, thyroid, kidney or liver problems; or if you are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. 

Tell your healthcare provider about all the medicines you take. BYNFEZIA PEN™ may affect the way other medicines work, and other medicines may affect how BYNFEZIA PEN™ works. If you have diabetes, your healthcare provider may change your dose of diabetes medication when you first start receiving BYNFEZIA PEN™ or if your dose of BYNFEZIA PEN™ is changed.

Especially tell your healthcare provider if you take:

  • Insulin or other diabetes medicines
  • Cyclosporine
  • Bromocriptine
  • Medicines that lower your heart rate, such as beta-blockers

These are not all the possible side effects of BYNFEZIA PEN™. For more information, ask your healthcare provider.

You are encouraged to report any negative side effects of BYNFEZIA PEN™ to the FDA. Visit www.fda.gov/watch or call 1-800-FDA-1088. You are also encouraged to report side effects or adverse drug events to our Drug Safety Department at 1-800-406-7984 or drug.safetyUSA@sunpharma.com (preferred) with as much information as available.

Please see Full Prescribing Information.

IMPORTANT SAFETY INFORMATION

INDICATIONS

BYNFEZIA PEN™ (octreotide acetate) injection is a prescription drug used:

  • Treatment of severe diarrhea/flushing episodes associated with metastatic carcinoid tumors in adult patients
  • Treatment of profuse watery diarrhea associated with vasoactive intestinal peptide tumors (VIPomas) in adult patients
  • To reduce the amount of growth hormone and insulin like growth factor 1 in adult patients with acromegaly who have had inadequate response to or cannot be treated with surgical resection, pituitary irradiation, and bromocriptine mesylate at maximally tolerated doses

LIMITATIONS OF USE

  • In patients with acromegaly, the effect of BYNFEZIA PEN™ to improve symptoms and reduce tumor size and rate of growth has not been determined
  • In patients with carcinoid syndrome and VIPomas, the effect of BYNFEZIA PEN™ on size, rate of growth, and development of metastases has not been determined

IMPORTANT SAFETY INFORMATION

CONTRAINDICATIONS

Do not use BYNFEZIA PEN™ if you are allergic to octreotide.

ADVERSE EFFECTS, WARNINGS AND PRECAUTIONS

BYNFEZIA PEN™ may cause serious adverse effects, including gallstones, high or low blood sugar, thyroid effects, and slow heart rate.  

Tell your healthcare provider if you have any of the following:

  • Signs or symptoms of gallstones (gallbladder/liver problems): May include unexplained pain in your upper right abdomen, sudden pain in your back/right shoulder or between your shoulder blades, yellowing of your skin and whites of your eyes, fever with chills, or severe nausea/vomiting
  • Signs or symptoms of high or low blood sugar: May include increased thirst, urination, appetite, nausea, weakness, or tiredness 
  • Signs or symptoms of low blood sugar: May include nervousness, shakiness, sweating, fast heartbeat, irritability or mood changes, and hunger
  • Signs or symptoms of slow heart rate: May include dizziness or lightheadedness, fainting or near fainting, chest pain, shortness of breath, confusion or memory problems, and weakness or extreme tiredness
  • Signs or symptoms of low thyroid levels: May include unexplained weight gain, cold intolerance, slow heartbeat, severe constipation, unusual/extreme tiredness, growth/lump/swelling on the front of the neck, numbness, or tingling feeling that is not normal

It is not known if BYNFEZIA PEN™ will harm your unborn baby or pass into breast milk.

The most common side effects of BYNFEZIA PEN™ are:

  • Acromegaly patients: Diarrhea, loose stools, nausea and stomach area (abdominal) pain
  • Carcinoid syndrome patients: Headache, dizziness, muscle spasm; side effects were generally similar to those commonly seen with neuroendocrine tumors

Tell your healthcare provider right away if you have signs of an allergic reaction after receiving BYNFEZIA PEN™. Symptoms include swelling of your face, lips or tongue, breathing problems, fainting, dizziness or feeling lightheaded (low blood pressure), itching, skin flushing or redness, rash, or hives.

Before taking BYNFEZIA PEN™, tell your healthcare provider about other medical conditions, especially if you have diabetes, gallbladder, heart, thyroid, kidney or liver problems; or if you are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. 

Tell your healthcare provider about all the medicines you take. BYNFEZIA PEN™ may affect the way other medicines work, and other medicines may affect how BYNFEZIA PEN™ works. If you have diabetes, your healthcare provider may change your dose of diabetes medication when you first start receiving BYNFEZIA PEN™ or if your dose of BYNFEZIA PEN™ is changed.

Especially tell your healthcare provider if you take:

  • Insulin or other diabetes medicines
  • Cyclosporine
  • Bromocriptine
  • Medicines that lower your heart rate, such as beta-blockers

These are not all the possible side effects of BYNFEZIA PEN™. For more information, ask your healthcare provider.

You are encouraged to report any negative side effects of BYNFEZIA PEN™ to the FDA. Visit www.fda.gov/watch or call 1-800-FDA-1088. You are also encouraged to report side effects or adverse drug events to our Drug Safety Department at 1-800-406-7984 or drug.safetyUSA@sunpharma.com (preferred) with as much information as available.

Please see Full Prescribing Information.

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